Boston Scientific - On Demand

PROACTIF Final HCC Results: Real-World Evidence

Redefining liver cancer care with Therasphere Y-90 Therapy

Survival Across BCLC Stages, Proven in Real-World

Backed by two decades of clinical experience, TheraSphere™ Y-90 Therapy continues to expand its evidence base – pushing treatment boundaries and redefining the standard in liver cancer care.

Final results from PROACTIF, the largest, prospective real-world Y-90 study, show meaningful survival across BCLC stages, including patients with PVT and those with intermediate and advanced disease.

See the Data

Now published in The Lancet’s eClinicalMedicine¹

PROACTIF highlights the value of TheraSphere™ Y-90 Therapy in HCC, demonstrating favorable effectiveness and safety with robust outcomes in an all-comers population over 5 years and reflective of real-world clinical practice complexity.

989 PATIENTS

across 34 SITES

MEDIAN OS

21.8 months
(95% CI: 20.1 – 23.3)

See the impactful survival outcomes - including in intermediate and advanced disease, patients with PVT, and large tumours - and the importance of the dose-survival relationship.

Uncover the Evidence

Explore clinical insights and emerging evidence.
Join our new dedicated Interventional Oncology and Embolisation LinkedIn page.

Boston Scientific International SA

www.bostonscientific.eu | Tel: +33 1 39 30 97 00

Parc Val Saint Quentin - Bâtiment H | 2 Rue René Caudron | 78960 Voisins-le-Bretonneux

VAT: FR07420668402

References

1. Guiu et al. Effectiveness and Safety of Selective Internal Radiation Therapy using Yttrium-90 Glass Microspheres for Hepatocellular Carcinoma: Real-world Results from the Multi-center Prospective PROACTIF Cohort of 989 Patients. eClinicalMedicine. Published Online https://doi.org/10.1016/j.eclinm.2026.103884

CAUTION

The law restricts these devices to sale by or on the order of a physician. Indications, contraindications, warnings, and instructions for use can be found in the product labelling supplied with each device or at www.IFU-BSCI.com.
Products shown for INFORMATION purposes only and may not be approved or for sale in certain countries.
This material is not intended for use in France.

PI-2487006-AA
CⲈ 0123

Privacy Policy | Terms of Use

For questions on privacy
Contact our EU Data Protection Officer at: [email protected]
Boston Scientific
c/Ribera del Loira, 46 Edificio 2
28042 Madrid (Spain)